Calendar of Events
Seminar: Biological discoveries using four dimensional biomaterials
Department of Chemistry and Biochemistry Seminar
Seminar topic: Biological Discoveries Using Four Dimensional Biomaterials.
Lecturer: Dr. Lou Gu, School of Engineering and Applied Sciences, Wyss Institute for Biologically Inspired Engineering, Harvard University
With recent advances in materials science and molecular biology, biomaterials have become important tools to study and engineer various biological processes. It has also become clear that how materials interact with biological systems highly depends on the dimensionality. For example, the use of 3D biomaterials as cell culture matrix has revealed new aspects of biology that were not captured with conventional 2D culture due to better recapitulation of cell microenvironment. However, cells and tissues are not only multi-dimensional in space, but are also dynamic and exhibit different characteristics over time. Therefore, four dimensional biomaterials with tunable temporal properties are needed to better study and engineer dynamic biological processes. In this talk, I will discuss two types of biomaterials (viscoelastic alginate hydrogels and luminescent silicon nanoparticles) which have attractive properties in the temporal dimension, and describe how their unique mechanical or optical properties are exploited for tissue regeneration or in vivo imaging, respectively.